CAG

🔍 Cagrilintide — Research Peptide

Cagrilintide is a synthetic research peptide and a long acting analogue of the hormone amylin. It has been developed to investigate pathways of appetite, satiety, energy balance, and metabolic regulation.

Research Focus & Mechanism

• It mimics endogenous amylin (islet amyloid polypeptide), which is secreted by pancreatic β cells along with insulin and plays a role in regulating food intake and gastric emptying. 

• Cagrilintide is modified for extended half life (due to fatty acid chain linking etc) so that it can serve in once weekly dosing models in research. 

• Through activation of the amylin receptor (and via cross activation of calcitonin receptors) it is studied for:

o increasing satiety / reducing appetite

o slowing gastric emptying

o influencing caloric intake, energy expenditure, and weight/fat mass in metabolic models

o potential synergy with GLP 1 receptor agonists in weight management research.

⚠️ Disclaimer & Research Use Only. Cagrilintide is supplied for laboratory research purposes only.

It is not approved for human use, consumption or medical treatment. Research models should follow proper lab protocols, institutional oversight, and regulatory compliance.